1197026-56-4Relevant articles and documents
Use of the SPhos ligand to suppress racemization in arylpinacolboronate ester Suzuki couplings involving α-amino acids. Synthesis of biaryl derivatives of 4-hydroxyphenylglycine, tyrosine, and tryptophan
Prieto, Monica,Mayor, Silvia,Lloyd-Williams, Paul,Giralt, Ernest
, p. 9202 - 9205 (2009)
(Chemical Equation Presented) α-Amino acid derivatives, particularly those of phenylglycine, can suffer significant racemization in Suzuki couplings. When arylpinacolboronate esters are used as coupling partners this unwanted side reaction can be suppress