1197208-64-2Relevant academic research and scientific papers
Long-Lived Polymer-Supported Dimeric Cinchona Alkaloid Organocatalyst in the Asymmetric α-Amination of 2-Oxindoles
Jumde, Ravindra P.,Mandoli, Alessandro
, p. 4281 - 4285 (2016)
Nearly quantitative yields and high enantiomeric purity (89-95% ee) were attained in the course of 100 reaction cycles of a polystyrene resin-supported Cinchona alkaloid organocatalyst in the enantioselective α-amination of 2-oxindoles with diethyl azodicarboxylate. The catalytic material proved stable for >5300 h operation time over 8 months.
Expanding the scope of cinchona alkaloid-catalyzed enantioselective α-aminations of oxindoles: A versatile approach to optically active 3-amino-2-oxindole derivatives
Bui, Tommy,Borregan, Mar,Barbas III, Carlos F.
experimental part, p. 8935 - 8938 (2010/03/04)
(Chemical Equation Presented) A cinchona alkaloid-catalyzed, highly enantioselective, α-amination of oxindoles has been developed. The reaction is general, operationally simple, and affords the desired products in high yields with good to excellent enanti
