1197208-65-3Relevant articles and documents
New polymer-supported mono- And bis-cinchona alkaloid derivatives: Synthesis and use in asymmetric organocatalyzed reactions
Jumde, Ravindra P.,Di Pietro, Anila,Manariti, Antonella,Mandoli, Alessandro
, p. 397 - 404 (2015)
The straightforward synthesis of polystyrene-supported Chinchona alkaloids and their application in the asymmetric dimerization of ketenes is reported. Six different immobilized derivatives, consisting of three dimeric and two monomeric 9-O ethers, were p
Long-Lived Polymer-Supported Dimeric Cinchona Alkaloid Organocatalyst in the Asymmetric α-Amination of 2-Oxindoles
Jumde, Ravindra P.,Mandoli, Alessandro
, p. 4281 - 4285 (2016/07/12)
Nearly quantitative yields and high enantiomeric purity (89-95% ee) were attained in the course of 100 reaction cycles of a polystyrene resin-supported Cinchona alkaloid organocatalyst in the enantioselective α-amination of 2-oxindoles with diethyl azodicarboxylate. The catalytic material proved stable for >5300 h operation time over 8 months.
Expanding the scope of cinchona alkaloid-catalyzed enantioselective α-aminations of oxindoles: A versatile approach to optically active 3-amino-2-oxindole derivatives
Bui, Tommy,Borregan, Mar,Barbas III, Carlos F.
supporting information; experimental part, p. 8935 - 8938 (2010/03/04)
(Chemical Equation Presented) A cinchona alkaloid-catalyzed, highly enantioselective, α-amination of oxindoles has been developed. The reaction is general, operationally simple, and affords the desired products in high yields with good to excellent enanti