119729-76-9

Upstream product

• 96720-08-0 ethyl (S,E)-5,6-dihydroxy-2-hexenoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 849418-94-6 (S)-(-)-β-tert-butyldiphenylsilyloxy-γ-butyrolactone 
• 96720-07-9 (E)-ethyl 4-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)but-2-enoate 
• 106401-45-0 (R)-[(2R,4S)-4-(tert-Butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-yl]-iodo-acetic acid ethyl ester 
• 106401-47-2 (S)-[(2R,4S)-4-(tert-Butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-yl]-iodo-acetic acid ethyl ester 

Downstream Products

• 849418-95-7 ethyl (2E)(5S)-5-tert-butyldiphenylsilyloxy-6-oxohex-2-enoate 
• 849419-05-2 (E)-(S)-5-(tert-Butyl-diphenyl-silanyloxy)-6-hydroxy-hept-2-enoic acid ethyl ester 
• 849418-96-8 ethyl (2E)(5S)-5-tert-butyldiphenylsilyloxy-6-oxohept-2-enoate 
• 849418-99-1 (2E,6E)(5S)-5-tert-butyldiphenylsilyloxy-6-methyl-7-{2-methyl-(1,3-thiazol-4-yl)}hepta-2,6-dienal 
• 849419-06-3 (2E,6E)(5S)-5-tert-butyldiphenylsilyloxy-6-methyl-7-{2-methyl-(1,3-thiazol-4-yl)}hepta-2,6-dien-1-ol 
• 849418-98-0 ethyl (2E,6E)(5S)-5-tert-butyldiphenylsilyloxy-6-methyl-7-{2-methyl-(1,3-thiazol-4-yl)}hepta-2,6-dienoate 
• 849419-01-8 (4R,5S,6S,7R,9R,16S)-7-{2-(tert-butyldiphenylsilyloxy)ethyl}-4,6-isopropylidenedioxy-5,9-dimethyl-{1-methyl-2-{2-methyl-(1,3-thiazol-4-yl)}-1(E)-ethenyl}-11(E),13(E)-diene-2,10-dione 
• 849419-00-7 4-formyl-1(R)-{1-methyl-2-[2-methyl(1,3-thiazol-4-yl)]-1(E)-ethenyl}-3-(E)-butenyl-(3R,4S,5S,6R,8R)-10-dimethoxyphosphono-6-{2-(tert-butyldiphenylsilyloxy)ethyl}-3,5-isopropylidenedioxy-3,8-dimethyl-9-oxodecanoate 

Relevant academic research and scientific papers

Design and synthesis of 16-membered hybrid macrolide having a thiazole side chain on the carbonolide skeleton

Design and synthesis of a 16-membered hybrid macrolide, which contained a 16-membered carbonolide-type lactone framework with a thiazole sidechain, were described.

EXCEPTIONALLY MILD AND STEREOSPECIFIC RING FRAGMENTATIONS PROMOTED BY DIMETHYLBORON BROMIDE

A stereospecific and exceptionally mild fragmentation of β-iodoethers and allylic iodoethers by Me2BBr in the presence of n-Bu4NI was developed

PREPARATION OF ETHYL 5(S),6-EPOXY-3(R)-(METHOXYMETHOXY)HEXANOATE: A KEY CHIRAL INTERMEDIATE FOR MEVINOLIN AND COMPACTIN.

The synthesis of Ethyl 5(S),6-Epoxy-3(R)-(methoxymethoxy)hexanoate, a key chiral synthon for the β-hydroxy-δ-lactone portion of Mevinolin and Compactin, via a regiospecific ring opening of a tetrahydrofuran derivative by dimethyboron bromide, is described.