(S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine, commonly known as loperamide, is a synthetic opioid compound that serves as an anti-diarrheal medication. It functions by reducing the speed of intestinal movement, which in turn decreases the frequency of bowel movements and lessens the water content in stool. Loperamide is accessible over-the-counter and is widely recognized for its safety and efficacy in treating acute diarrhea. However, it is crucial to adhere to the prescribed dosage and consult a medical professional if symptoms continue or escalate, as misuse of loperamide can lead to severe and potentially fatal consequences, including respiratory depression and other opioid-related side effects.
119746-92-8
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Basic information
- Product Name: (S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine
- Synonyms:
- CAS NO:119746-92-8
- Molecular Formula:
- Molecular Weight: 184.622
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine(CAS DataBase Reference)
- NIST Chemistry Reference: (S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine(119746-92-8)
- EPA Substance Registry System: (S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine(119746-92-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 119746-92-8(Hazardous Substances Data)
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119746-92-8 Usage
Uses
Used in Pharmaceutical Industry:(S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine is used as an active pharmaceutical ingredient for the treatment of acute diarrhea. It is effective in slowing down the intestinal motility, which helps in reducing the frequency of bowel movements and the watery consistency of stool. As an over-the-counter medication, it provides a convenient and accessible solution for managing diarrhea symptoms.
Used in Medical Research:
In addition to its practical applications, (S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine, or loperamide, is also utilized in medical research to study the effects and mechanisms of synthetic opioids on the human body. This research can contribute to the development of new medications and a better understanding of the risks and benefits associated with opioid use.
Used in Public Health and Safety Education:
Loperamide serves as a cautionary example in public health and safety education, highlighting the importance of responsible medication use and the potential dangers of misuse and abuse. By informing the public about the risks associated with loperamide, educational initiatives can help prevent overdoses and promote safe medication practices.
Check Digit Verification of cas no
The CAS Registry Mumber 119746-92-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,7,4 and 6 respectively; the second part has 2 digits, 9 and 2 respectively.Calculate Digit Verification of CAS Registry Number 119746-92:
(8*1)+(7*1)+(6*9)+(5*7)+(4*4)+(3*6)+(2*9)+(1*2)=158
158 % 10 = 8
So 119746-92-8 is a valid CAS Registry Number.
119746-92-8Upstream product
119746-92-8Downstream Products
- 119746-72-4 (S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-{[(R)-1-(2,3-dihydro-benzo[1,4]dioxin-2-yl)methyl]-methyl-amino}-ethyl) ester 5-methyl ester
- 119746-76-8 (R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-{[(R)-1-(2,3-dihydro-benzo[1,4]dioxin-2-yl)methyl]-methyl-amino}-ethyl) ester 5-methyl ester
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(S)-2-(chloromethyl)-2,3-dihydrobenzo[b][1,4]dioxine
