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TAUTOMYCETIN SOLUTION is a complex organic compound that has been identified for its potential applications in both cancer treatment and immunosuppression. It is an anhydride-containing polyketide PP inhibitor, closely related to Tautomycetin, and has demonstrated the ability to induce apoptosis in human breast cancer cells by inactivating the Akt pathway through a PP1-independent signaling mechanism.

119757-73-2

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119757-73-2 Usage

Uses

Used in Cancer Treatment Applications:
TAUTOMYCETIN SOLUTION is used as an anticancer agent for its ability to induce apoptosis in cancer cells, specifically targeting human breast cancer cells. It operates through a unique PP1-independent signaling pathway that inactivates the Akt pathway, which plays a crucial role in cell survival and growth.
Used in Immunosuppression Applications:
In addition to its cancer treatment potential, TAUTOMYCETIN SOLUTION is also recognized as a potent immunosuppressor. This characteristic makes it a valuable compound for applications where dampening the immune response is necessary, such as in the prevention of transplant rejection or the treatment of autoimmune diseases.
Used in Drug Discovery:
Given its significant biological activities, TAUTOMYCETIN SOLUTION serves as a promising lead compound in the discovery and development of new drugs for cancer treatment and immunosuppression. Its unique mechanism of action and potential for synergistic effects with other therapeutic agents make it an attractive candidate for further research and pharmaceutical innovation.

Biological Activity

Potent activated T cell-specific immunosuppressor. Selectively inhibits PP1 over PP2 with IC 50 values of 1.6 and 62 nM respectively. Active in vivo .

Check Digit Verification of cas no

The CAS Registry Mumber 119757-73-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,7,5 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 119757-73:
(8*1)+(7*1)+(6*9)+(5*7)+(4*5)+(3*7)+(2*7)+(1*3)=162
162 % 10 = 2
So 119757-73-2 is a valid CAS Registry Number.
InChI:InChI=1/C33H50O10/c1-9-24(10-2)15-25(34)14-19(4)13-18(3)11-12-26(35)21(6)28(37)16-27(36)20(5)23(8)42-30(39)17-29(38)31-22(7)32(40)43-33(31)41/h9,15,18-21,23,26-27,29,35-36,38H,1,10-14,16-17H2,2-8H3/b24-15-

119757-73-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Tautomycetin

1.2 Other means of identification

Product number -
Other names Taurohyodesoxycholsaeure

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119757-73-2 SDS

119757-73-2Upstream product

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