119779-12-3

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-chloroethyl)-2-fluorobenzene is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(2-chloroethyl)-2-fluorobenzene serves as a precursor in the production of agrochemicals, which are essential for crop protection and enhancement of agricultural yields.
Used in Dye Industry:
1-(2-chloroethyl)-2-fluorobenzene is utilized as an intermediate in the synthesis of dyes, playing a crucial role in the creation of colorants for various applications, including textiles, plastics, and printing inks.
Used in Organic Chemicals and Polymers Production:
1-(2-chloroethyl)-2-fluorobenzene is employed in the production of organic chemicals and polymers, which have a wide range of applications across different industries, from plastics to coatings and adhesives.
Safety Considerations:
Due to its flammable nature and potential to cause irritation to the skin, eyes, and respiratory system, as well as its adverse effects on aquatic life, 1-(2-chloroethyl)-2-fluorobenzene requires careful handling and proper disposal procedures to ensure safety and environmental protection.

Upstream product

• 593-71-5 Chloroiodomethane 
• 446-52-6 2-Fluorobenzaldehyde 
• 50919-06-7 2-(2-fluorophenyl)ethanol 

Downstream Products

• 1026468-91-6 2-{1-[2-(2-Fluoro-phenyl)-ethyl]-piperidin-4-yl}-1H-benzoimidazole 
• 1236156-83-4 2-((2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)(2-fluorophenethyl)amino)acetonitrile 
• 1236156-81-2 2-(2,4-difluorophenyl)-1-((2-fluorophenethyl)(prop-2-ynyl)amino)-3-(1H-1,2,4-triazol-1-yl)propan-2-ol 
• 406721-71-9 2-(5-chloro-2-((2-fluorophenethyl)oxy)phenyl)-1-(1H-1-imidazolyl)-2-pentanol 

Relevant academic research and scientific papers

Chemoselective Homologation-Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into (n+1)-Halomethyl-Alkanes

The sequential installation of a carbenoid and a hydride into a carbonyl, furnishing halomethyl alkyl derivatives, is reported. Despite the employment of carbenoids as nucleophiles in reactions with carbon-centered electrophiles, sp3-type alkyl halides remain elusive materials for selective one-carbon homologations. Our tactic levers on using carbonyls as starting materials and enables uniformly high yields and chemocontrol. The tactic is flexible and is not limited to carbenoids. Also, diverse carbanion-like species can act as nucleophiles, thus making it of general applicability.

Pyrrolo[2,3-d] pyrimidines as antiviral agents

This invention relates to a novel class of 4,5,6,7-substituted non-nucleoside, non-phosphorylatable pyrrolo[2,3-d]pyrimidines which exhibit both significantly lower levels of cytotoxicity and superior antiviral activity than known nucleoside, non-nucleoside, and non-nucleoside, non-phosphorylatable pyrrolo[2,3-d]pyrimidine derivatives, particularly against human DNA viruses such as cytomegalovirus (HCMV) and herpes simplex virus type 1 (HSV-1). These compounds are represented by the following formula: wherein: R4is —NR1R2or oxo; R5is —CN, or —CSNR1R2, or —CONR1R2; R6is —H, or halo, or —NR1R2; wherein R1and R2are independently —H or an aliphatic group; and R7is of the formula R3—Ar, wherein R3is an aliphatic group and Ar is an unsubstituted aryl or an aryl independently substituted with halo, nitro, amino, or aliphatic groups; provided that when R5is a —CN or —CSNH2, and R6is a —H or —NH2, and Ar is a —C6H5or a phenyl substituted with only one aliphatic group, R3is an aliphatic group other than methyl such that —R3— is not a —CH2—; and pharmaceutically acceptable salts, prodrugs and derivatives thereof.