1197860-99-3Relevant academic research and scientific papers
Efficient synthesis of 5-alkoxy-(3r)-hydroxy-2,3-dihydrospiro[indene-1, 4?-piperidines]: A novel scaffold for renin inhibitors
Nakamura, Yuji,Jojima, Takaaki,Suzuki, Chie,Miyazaki, Shojiro,Nishi, Takahide
scheme or table, p. 2521 - 2523 (2010/01/16)
We report herein, an efficient synthetic method for the preparation of a 5-alkoxy-(3R)-hydroxy-2,3-dihydrospiro[indene-1,4-piperidines] scaffold using a regioselective intermolecular ?reaction and a stereoselective reduction as key steps. Compound 2, base
