119794-51-3

Basic information

• Product Name: 2'-TBDMS-Ac-rC
• Synonyms: 2'-TBDMS-Ac-rC;N-Acetyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine;2-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine;N4-Acetyl-2'-O-tert-butyldimethylsilyl-cytidine 2'-TBDMS-Ac-rC
• CAS NO: 119794-51-3
• Molecular Formula: C₁₇H₂₉N₃O₆Si
• Molecular Weight: 399.51
• EINECS: -0
• Mol File: 119794-51-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-TBDMS-Ac-rC(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-TBDMS-Ac-rC(119794-51-3)
• EPA Substance Registry System: 2'-TBDMS-Ac-rC(119794-51-3)

Safety Data

• Hazardous Substances Data: 119794-51-3(Hazardous Substances Data)

Usage

General Description

2'-TBDMS-Ac-rC, also known as 2'-O-tert-butyldimethylsilyl-N-acetyl-ribocytidine, is a modified nucleoside that is commonly used in biochemical and pharmaceutical research. It is a derivative of ribocytidine, a component of RNA, and is modified with a tert-butyldimethylsilyl group and an acetyl group at the 2'- position. This modification enhances the stability and selectivity of the nucleoside, making it useful for various applications such as RNA sequencing, structural studies, and the development of nucleoside analogs for antiviral and anticancer therapies. 2'-TBDMS-Ac-rC is often synthesized through chemical or enzymatic methods and has been studied for its potential in improving the properties and functionality of nucleic acids.

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 54925-64-3 N-(tert-butyldimethylsilyl)imidazole 
• 3768-18-1 N-acetylcytidine 

Relevant articles and documents

General syntheses of 2',3'-dideoxynucleosides and 2',3'-didehydro-2',3'-dideoxynucleosides

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