1197983-15-5Relevant articles and documents
Palladium-catalyzed enantioselective addition of two distinct nucleophiles across alkenes capable of quinone methide formation
Jensen, Katrina H.,Pathak, Tejas P.,Zhang, Yang,Sigman, Matthew S.
, p. 17074 - 17075 (2009)
(Chemical Equation Presented) A sequential intramolecular-intermolecular enantioselective alkene difunctionalization reaction has been developed which is thought to proceed through Pd-catalyzed quinone methide formation. The synthesis of new chiral heterocyclic compounds with adjacent chiral centers is achieved in enantiomeric ratios up to 99:1 and diastereomeric ratios up to 10:1.