1198-07-8Relevant academic research and scientific papers
Amino Acids, 10. - Reactions of 5-Oxoproline Derivatives with Thionyl and Oxalyl Chloride
Mueller, Wolfgang,Dorsch, Werner,Effenberger, Franz
, p. 55 - 60 (2007/10/02)
Reactions of N-methyl- and N-benzyl-substituted 5-oxoproline methylesters (1a,b) with thionyl or oxalyl chloride yield N-substituted 5-chloro-2,3-dihydro-1H-pyrrole-2-carboxylic esters.These esters, as α-chloro enamines, undergo further electrophilic reac
