119807-84-0Relevant academic research and scientific papers
COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS
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Page/Page column 207, (2010/06/22)
The present invention is directed to novel compounds of formula (I) and their use in treating metabolic diseases.
Asymmetric hydrogenation of itaconic acid and enol acetate derivatives with the Rh-TangPhos catalyst
Tang, Wenjun,Liu, Duan,Zhang, Xumu
, p. 205 - 207 (2007/10/03)
(Matrix presented) The Rh-TangPhos catalyst has been used for asymmetric hydrogenation of itaconic acid and enol acetate derivatives. A variety of chiral 2-substituted succinic acids and chiral acetates have been obtained in excellent ee values (up to 99% ee).
Practical access to 2-alkylsuccinates through asymmetric catalytic hydrogenation of Stobbe-derived itaconates
Burk, Mark J.,Bienewald, Frank,Harris, Michael,Zanotti-Gerosa, Antonio
, p. 1931 - 1933 (2007/10/03)
Enantiomerically pure 2-alkylsuccinates are obtained on a 500-g scale after hydrogenation with the cationic rhodium complexes with tetraalkyl-substituted 1,2-bis(phospholanyl)ethane or -benzene ligands [R'-DuPHOS; Eq. (a)]. The catalysts allow smooth hydr
