1198080-11-3 Usage
Uses
Used in Pharmaceutical Synthesis:
Tert-butyl (S)-2-(hydroxymethyl)aziridine-1-carboxylate is used as a key intermediate for the synthesis of various pharmaceuticals. Its chiral center and aziridine ring contribute to the development of biologically active compounds, making it a valuable component in the creation of new drugs.
Used in Agrochemical Synthesis:
In the agrochemical industry, tert-butyl (S)-2-(hydroxymethyl)aziridine-1-carboxylate is utilized as a crucial intermediate for the synthesis of various agrochemicals. Its unique structural features enable the development of effective pesticides and other agricultural chemicals.
Used in Asymmetric Synthesis:
Due to its chiral center, tert-butyl (S)-2-(hydroxymethyl)aziridine-1-carboxylate is employed as a reagent in asymmetric synthesis. This allows for the selective formation of enantiomerically pure compounds, which is crucial in the production of pharmaceuticals and other chiral molecules with specific biological activities.
Used in the Preparation of Biologically Active Compounds:
Tert-butyl (S)-2-(hydroxymethyl)aziridine-1-carboxylate is used as a reagent in the preparation of biologically active compounds. Its aziridine ring provides a versatile platform for the construction of complex molecules with potential therapeutic or pesticidal properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1198080-11-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,8,0,8 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1198080-11:
(9*1)+(8*1)+(7*9)+(6*8)+(5*0)+(4*8)+(3*0)+(2*1)+(1*1)=163
163 % 10 = 3
So 1198080-11-3 is a valid CAS Registry Number.
1198080-11-3Relevant academic research and scientific papers
LZC696 intermediate and synthetic method therefor
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Paragraph 0074; 0075, (2016/10/09)
The invention discloses a compound which is (R)-tert-butyl(1,((1,1'biphenyl)-4-yl)3-((t-butyldimethylsilyl)oxo)propane-2-yl)carbamate, and the structural formula of the compound is as shown in formula A in the specification. An LZC696 intermediate is synthetized by adopting the compound, the whole technological process is free of expensive reagents or raw materials, free of sensitive reaction for oxygen and simple in purifying procedure, and commercial using purity can be achieved only by recrystallization purification of the compound 3 and the final product. The synthetic process of the invention is low in cost, simple and environmentally-friendly, and is suitable for industrial mass production.
Enantioselective aziridination reaction of α,β-unsaturated aldehydes using an organocatalyst and tert-butyl N-arenesulfonyloxycarbamates
Arai, Hiromi,Sugaya, Naomi,Sasaki, Neri,Makino, Kazuishi,Lectard, Sylvain,Hamada, Yasumasa
scheme or table, p. 3329 - 3332 (2009/09/05)
An organocatalytic enantioselective aziridination reaction of α,β-unsaturated aldehydes including aromatic substrates using N-arenesulfonyloxycarbamates in the presence of diphenylprolinol triethylsilyl ether and sodium carbonate or sodium acetate is desc
Asymmetrie total syntheses of (-)-renieramycin M and G and (-)-jorumycin using aziridine as a lynchpin
Wu, Yan-Chao,Zhu, Jieping
supporting information; experimental part, p. 5558 - 5561 (2010/02/28)
"Chemical Equation Presented" By exploring the triple reactivity of two aziridines and double nucleophilicity of two aromatics, convergent and versatile syntheses of the above four natural products were developed.
