1198157-08-2Relevant academic research and scientific papers
HEPARAN SULFATE SYNTHESIS
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Page/Page column 30; 93, (2010/11/03)
The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in
Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies
Arungundram, Sailaja,Al-Mafraji, Kanar,Asong, Jinkeng,Leach III, Franklin E.,Amster, I. Jonathan,Venot, Andre,Turnbull, Jeremy E.,Boons, Geert-Jan
supporting information; experimental part, p. 17394 - 17405 (2010/03/23)
Although hundreds of heparan sulfate binding proteins have been identified and implicated in a myriad of physiological and pathological processes, very little information is known about the ligand requirements for binding and mediating biological activiti
