1198174-41-2Relevant academic research and scientific papers
Tricyclic 3,4-dihydropyrimidine-2-thione derivatives as potent TRPA1 antagonists
Gijsen, Harrie J.M.,Berthelot, Didier,De Cleyn, Michel A.J.,Geuens, Ivo,Brone, Bert,Mercken, Marc
scheme or table, p. 797 - 800 (2012/03/11)
The transient receptor potential A1 (TRPA1) channel has been implicated in a number of inflammatory and nociceptive processes, and antagonists of the TRPA1 receptor could offer a potential treatment for conditions such as inflammatory or neuropathic pain,
3,4-DIHYDROPYRIMIDINE TRPA1 ANTAGONISTS
-
Page/Page column 25-26, (2009/12/28)
The present invention is related to novel 3,4-dihydropyrimidine compounds of formula (I) having TRPA1 receptor antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use
