1198184-07-4

Basic information

• Product Name: [1,1'-biphenyl]-4-yl 1H-imidazole-1-sulfonate
• Synonyms: [1,1'-biphenyl]-4-yl 1H-imidazole-1-sulfonate
• CAS NO: 1198184-07-4
• Molecular Weight: 300.338
• Mol File: 1198184-07-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [1,1'-biphenyl]-4-yl 1H-imidazole-1-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-biphenyl]-4-yl 1H-imidazole-1-sulfonate(1198184-07-4)
• EPA Substance Registry System: [1,1'-biphenyl]-4-yl 1H-imidazole-1-sulfonate(1198184-07-4)

Safety Data

• Hazardous Substances Data: 1198184-07-4(Hazardous Substances Data)

Upstream product

• 92-69-3 4-Phenylphenol 
• 7189-69-7 N,N`-sulfuryldiimidazole 
• 98-80-6 phenylboronic acid 

Downstream Products

• 17064-45-8 2-(4-biphenylyl)benzoxazole 

Relevant articles and documents

Synthesis of 18F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination

Sulfuryl fluoride gas is a key reagent for SO2F transfer. However, conventional SO2F transfer reactions have limited 18F-radiochemistry translation, due to the inaccessibility of gaseous [18F]SO2F2. Herein, we report the first SO2F2-free synthesis of aryl [18F]fluorosulfates from both phenolic and isolated aryl imidazylate precursors with cyclotron-produced 18F-. The radiochemical yields ranged from moderate to good with excellent functional group tolerance. The reliability of our approach was validated by the automated radiosynthesis of 4-acetamidophenyl [18F]fluorosulfate.

Microwave-promoted suzuki-miyaura cross-coupling of aryl imidazolylsulfonates in water

Aryl imidazol-1-ylsulfonates are efficiently cross-coupled with potassium aryl- and alkenyltrifluoroborates in neat water under microwave heating (40 W, 110°C) using 0.5 mol% of oxime palladacycle 1a, hexadecyltrimethyl ammonium bromide (CTAB) as additive, and triethylamine as base. Under these simple phosphane-free reaction conditions a wide array of biaryl, stilbene and styrene derivatives has been prepared in good to high yields and with high regio- and diastereoselectivities in only 30 min.