1198184-97-2Relevant academic research and scientific papers
Synthesis of cyclopamine using a biomimetic and diastereoselective approach
Giannis, Athanassios,Heretsch, Philipp,Sarli, Vasiliki,Stoessel, Anne
supporting information; experimental part, p. 7911 - 7914 (2010/03/30)
From Homer to hedgehog: Cyclopamine, the first inhibitor of the hedgehog signaling pathway, causes cyclopia in embryos butin adults it is a potent anticancer drug. A concise biomimetic and diastereoselective synthesis of cyclopamine (2) starting from comm
