119825-84-2

Upstream product

• 68001-80-9 (E)-3-(4-Chloro-phenyl)-2-formylamino-acrylic acid methyl ester 
• 68001-79-6 (Z)-3-(4-Chloro-phenyl)-2-formylamino-acrylic acid methyl ester 
• 120301-93-1 (Z)-3-(4-Chloro-phenyl)-2-formylamino-acrylic acid methyl ester 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 119826-06-1 (Z)-methyl β-bromo-α-isocyano-(4-chloro)cinnamate 
• 119825-95-5 (E)-3-(4-Chloro-phenyl)-3-ethylsulfanyl-2-formylamino-acrylic acid methyl ester 
• 119825-96-6 (E)-3-(4-Chloro-phenyl)-3-ethylsulfanyl-2-formylamino-acrylic acid methyl ester 
• 119826-07-2 benzyl (E)-β-benzyloxy-α-isocyano-(4-chloro)cinnamate 
• 119825-99-9 benzyl (E)-β-benzyloxy-α-formylamino-(4-chloro)cinnamate 
• 119826-12-9 methyl 3-(4 chlorophenyl)-2-isocyano-3,3-dimethoxypropionate 
• 119826-04-9 N-[2-(4-chlorophenyl)-1-methoxycarbonyl-2-oxoethyl]formamide 

Relevant academic research and scientific papers

A Novel Synthesis of Methyl 5-Substituted Thiazole-4-carboxylates Using 3-Bromo-2-isocyanoacrylates (BICA)

A novel synthetic method for methyl 5-substituted thiazole-4-carboxylates (5) by the reaction of methyl 3-substituted 3-bromo-2-isocyanoacrylates (BICA) (1) with hydrogen sulfide in the presence of triethylamine in N,N-dimethylformamide was explored, and

SYNTHESIS OF Β-FUNCTIONALIZED α,β-DEHYDROAMINO ACID DERIVATIVES

β-functionalized α,β-unsaturated amino acids were synthesized by an addition-elimination pathway.Reaction of methyl β-bromo-α-formylaminoacrylates ( 3a-e ), which were prepared by the condensation of methyl isocyanoacetate ( 1 ) with aldehydes followed by