1198362-25-2Relevant academic research and scientific papers
Highly efficient asymmetric organocatalytic Michael addition of α,α-disubstituted aldehydes to nitroolefins under solvent-free conditions
He, Junpeng,Chen, Qiankun,Ni, Bukuo
supporting information, p. 3030 - 3032 (2014/05/20)
A chiral pyrrolide-based diamine in combination with benzoic acid has been found to be an effective organocatalyst for Michael addition of α,α-disubstituted aldehydes with nitroolefins. The reaction provided the desired Michael products possessing all-car
Pyrrolidinyl-camphor derivatives as a new class of organocatalyst for direct asymmetric Michael addition of aldehydes and ketones to β-nitroalkenes
Ting, Ying-Fang,Chang, Chihliang,Reddy, Raju Jannapu,Magar, Dhananjay R.,Chen, Kwunmin
supporting information; experimental part, p. 7030 - 7038 (2010/08/03)
Practical and convenient synthetic routes have been developed for the synthesis of a new class of pyrrolidinyl-camphor derivatives (7a-h). These novel compounds were screened as catalysts for the direct Michael addition of symmetrical αα-disubstituted ald
Pyrrolidine-camphor derivative as an organocatalyst for asymmetic michael additions of α,α-disubstituted aldehydes to β-nitroalkenes: Construction of quaternary carbon-bearing aldehydes under solvent-free conditions
Chang, Chihliang,Li, Ssu-Hsien,Reddy, Raju Jannapu,Chen, Kwunmin
experimental part, p. 1273 - 1278 (2009/12/22)
A novel pyrrolidine-camphor organocatalyst 3 was designed, synthesized and proven to be an efficient catalyst for the asymmetric Michael reaction. Treatment of α,α-disubstituted aldehydes with β-nitroalkenes in the presence of 20 mol% organocatalyst 3 and
