119838-37-8

Basic information

• Product Name: (R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate
• Synonyms: (R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate
• CAS NO: 119838-37-8
• Molecular Formula: C₈H₈O₃*C₈H₁₆N₂O
• Molecular Weight: 308.37276
• Mol File: 119838-37-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate(119838-37-8)
• EPA Substance Registry System: (R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate(119838-37-8)

Safety Data

• Hazardous Substances Data: 119838-37-8(Hazardous Substances Data)

Usage

General Description

"(R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate" is a chemical compound that belongs to the class of imidazolidinones. It is a chiral molecule with a tert-butyl and a methyl group attached to the imidazolidinone ring. The compound also contains a phenyl group and a hydroxy group, which are attached to the carbon atom. This chemical may have potential applications in pharmaceuticals, agrochemicals, and materials science. Additionally, its chiral nature makes it useful for asymmetric synthesis and as a chiral ligand in catalytic reactions. Further research and development of this compound could lead to the discovery of new drugs and materials with unique properties and applications.

Upstream product

• 611-71-2 (R)-Mandelic Acid 
• 101055-55-4 (+/-)-2-(tert-butyl)-3-methylimidazolidin-4-one 

Downstream Products

• 119838-35-6 (2S,5S)-1-benzoyl-2-t-butyl-5-(2-hydroxyethyl)-3-methyl-4-imidazolidinone 
• 101055-56-5 (2S)-1-benzoyl-2-(1,1-dimethylethyl)-3-methyl-4-imidazolidinone 
• 119838-38-9 (2S)-1-(tert-butyloxycarbonyl)-2-tert-butyl-3-methylimidazolidin-4-one 

Relevant articles and documents

RESOLUTION AND USE IN α-AMINO ACID SYNTHESIS OF IMIDAZOLIDINONE GLYCINE DERIVATIVES

The imidazolidinones (rac.-1 and rac.-2) obtained from pivalaldehyde and glycine amides are resolved efficiently by crystallization of diastereomeric ammonium salts with chiral acids (mandelates and a gulonate respectively).The free bases are acylated under Schotten-Baumann conditions to give enantiomerically pure 1-Bz-, 1-BOC-, 1-Z- or 1-formyl-2-t-butyl-3-methyl- or -3-benzyl-4-imidazolidinones.Diastereoselective alkylation of the 3-methyl derivatives (BMI) with a variety of electrophiles (LDA/THF -70 to +25 degC) gives trans-disubstituted imidazolidinones exclusively (3-22).Some of these are hydrolyzed by a procedure employing excess acidic ion exchange resin to give enantiomerically pure (R)- or (S)-amino acids.The procedure is compared with other methods of generating chiral glycine enolates.