119840-40-3Relevant academic research and scientific papers
Regio- and stereoselectivity in palladium-catalyzed cycloreductions of 1,6-enynes in the presence of formic acid or triethylsilane
Oh, Chang Ho,Jung, Hyung Hoon,Sung, Hye Rhyan,Kim, Jung Duk
, p. 1723 - 1729 (2001)
Palladium catalyzed 1,6-enyne cycloreductions in the presence of 1.2 equiv. of formic acid (method A) would involve cycloalkylpalladium formates which proceed via two consecutive steps: β-elimination of alkylpalladium intermediates and then reduction at t
A short synthesis of (±)-laurene: Mechanistic reinvestigation in palladium-catalyzed cycloreductions of 1,6-enynes
Chang Ho Oh,Je Wook Han,Joo Sung Kim,Sung Yong Um,Hyung Hoon Jung,Won Hyung Jang,Ho Shik Won
, p. 8365 - 8369 (2007/10/03)
Two palladium-catalyzed cycloreduction strategies have been applied for the synthesis of laurene. Palladium-catalyzed cyclizations of 1,6-enynes initially form the corresponding alkylpalladium intermediates. While triethylsilane could directly reduce the intermediates to lead to the corresponding cycloreduced products, the intermediates in the presence of even excess formic acid underwent β-elimination to yield the dienes that were further reduced at the less hindered olefins to yield the cycloreduced products. (C) 2000 Elsevier Science Ltd.
Reductive elimination of alkylpalladium formate intermediates formed in enyne cyclizations
Oh, Chang Ho,Jung, Hyung Hoon
, p. 1535 - 1538 (2007/10/03)
Various enynes under the palladium catalysts were successfully cyclized to the alkylpalladium intermediates, which then were reduced by the hydrogen in a formate ligand.
