119841-75-7Relevant academic research and scientific papers
Synthesis, cytotoxicity and antiviral activity of podophyllotoxin analogues modified in the E-ring
Castro, M. Angeles,Miguel Del Corral, Jose M.,Gordaliza, Marina,Gomez-Zurita, M. Antonia,De La Puente, M. Luz,Betancur-Galvis, Liliana A.,Sierra, Jelver,San Feliciano, Arturo
, p. 899 - 911 (2007/10/03)
Several podophyllotoxin derivatives modified in the E-ring were prepared and evaluated for their cytotoxicity on four neoplastic cell lines (P-388, A-549, HT-29 and MEL-28) and for their antiherpetic activity against Herpes simplex virus type II. The trim
Lignans and Related Phenols. Part 18. The Synthesis of Quinones from Podophyllotoxin and its Analogues
Ayres, David C.,Ritchie, Timothy J.
, p. 2573 - 2578 (2007/10/02)
The preparation of quinones from podophyllotoxin and peltatins of the aryltetrahydronaphtalene class by oxidative demethylation is described.The derivation of 2'-substituted ortho-quinones from these products by the reductive addition of azide, bromide, a
