119844-67-6

Basic information

• Product Name: (5R)-5-methylmorpholin-3-one
• Synonyms: (5R)-5-methylmorpholin-3-one;(5R)-5-Methyl-3-Morpholinone;(R)-5-Methylmorpholin-3-one;(R)-5-Methyl-3-morpholinone;(R)-5-Methyl-3-morpholinone,99%e.e.
• CAS NO: 119844-67-6
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115
• Mol File: 119844-67-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 290.934°C at 760 mmHg
• Flash Point: 129.752°C
• Appearance: /
• Density: 1.046g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.427
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (5R)-5-methylmorpholin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-5-methylmorpholin-3-one(119844-67-6)
• EPA Substance Registry System: (5R)-5-methylmorpholin-3-one(119844-67-6)

Safety Data

• Hazardous Substances Data: 119844-67-6(Hazardous Substances Data)

Usage

General Description

(5R)-5-methylmorpholin-3-one is a chemical compound with the molecular formula C5H9NO2. Also known as (R)-N-methyl-3-morpholinone, it is a cyclic amine and a morpholine derivative. (5R)-5-methylmorpholin-3-one is commonly used as a reagent in organic synthesis and as a building block for the production of pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a valuable tool in the development of new chemical compounds and materials. The (5R)-5-methylmorpholin-3-one molecule has potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science. Its properties and potential uses make it a valuable and versatile compound in the field of organic chemistry.

InChI:InChI=1/C5H9NO2/c1-4-2-8-3-5(7)6-4/h4H,2-3H2,1H3,(H,6,7)/t4-/m1/s1

Upstream product

• 35320-23-1 (R)-2-aminopropan-1-ol 
• 105-39-5 chloroacetic acid ethyl ester 
• 1057322-63-0 2-chloro-N-(2-hydroxy-1-methyl-ethyl)-acetamide 
• 542-58-5 2-chloro-1-acetoxyethane 

Downstream Products

• 1319196-77-4 (R)-4-(6-bromo-2-(4-methoxybenzylamino)quinolin-3-yl)-5-methylmorpholin-3-one 
• 1319194-41-6 (R)-(2-(2-amino-3-(3-methylmorpholino)quinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319196-79-6 (R)-N-(4-methoxybenzyl)-3-(3-methylmorpholino)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2-amine 
• 1319196-78-5 (R)-6-bromo-N-(4-methoxybenzyl)-3-(3-methylmorpholino)quinolin-2-amine 
• 74572-04-6 (3R)-3-methylmorpholine 

Relevant articles and documents

PYRAZOLOPYRIMIDINE DERIVATIVE AS SELECTIVE TRK INHIBITOR

The present invention discloses a compound of formula (II), a tautomer thereof or a pharmaceutically acceptable salt thereof, and relates to use thereof in preparing a medicament for treating solid tumor-related diseases.

A concise and efficient synthesis of substituted morpholines

A simple and efficient method has been developed for the synthesis of substituted morpholines by a sequence of coupling, cyclization, and reduction reactions of easily available amino alcohols and α-halo acid chlorides. Various mono-, di-, and trisubstituted morpholines, spiro morpholines, and ring-fused morpholines, as well as morpholine homologues, were synthesized in good to excellent yields by a single methodology under similar reaction conditions. The method was also used in a multigram synthesis of (3S)-3-methylmorpholine.

PYRAZOLE DERIVATIVE

A compound represented by Formula (I): wherein Ar1 represents Formula (II): Ar2 represents a 5- or 6-membered aromatic heterocyclic group which may be substituted; and X represents Formula (III): a salt thereof, or a solvate of the compound or the salt. A potent platelet aggregation suppressant which does not inhibit COX-1 and COX-2 is provided.