1198565-46-6Relevant articles and documents
Regioselective synthesis of poly-substituted thiophenes from Baylis-Hillman adducts
Lee, Hyun Seung,Kim, Se Hee,Kim, Jae Nyoung
scheme or table, p. 6480 - 6483 (2011/02/21)
The reaction of Baylis-Hillman acetates and ethyl mercaptoacetat e in the presence of DBU in DMF produced 2,3,4-trisubstituted tetrahydrothiophenes at room temperature as a diastereomeric mixture via the sequential SN2' and Michael addition. Aromatization of tetrahydrothiophenes by DDQ oxidation produced 2,3,4-trisubstituted thiophenes in good yields.