119866-82-9

Basic information

• Product Name: methyl 2-(benzylamino)-3,3,3-trifluoro-2-hydroxypropionate
• Synonyms: methyl 2-(benzylamino)-3,3,3-trifluoro-2-hydroxypropionate
• CAS NO: 119866-82-9
• Molecular Weight: 263.216
• Mol File: 119866-82-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 2-(benzylamino)-3,3,3-trifluoro-2-hydroxypropionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(benzylamino)-3,3,3-trifluoro-2-hydroxypropionate(119866-82-9)
• EPA Substance Registry System: methyl 2-(benzylamino)-3,3,3-trifluoro-2-hydroxypropionate(119866-82-9)

Safety Data

• Hazardous Substances Data: 119866-82-9(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 864366-06-3 methyl 2-anilino-3,3,3-trifluoro-2-hydroxypropanoate 
• 13089-11-7 methyl 3,3,3-trifluoropyruvate 

Downstream Products

• 404576-82-5 2-Hydroxy-2-(cyclopentanon-2-yl)-trifluorpropionic acid methyl ester 
• 126402-01-5 2-Hydroxy-2-trifluoromethyl-4-oxo-4-phenylbutanoic acid methyl ester 
• 118163-50-1 2-Hydroxy-2-trifluormethyl-4-oxopentanoic acid methyl ester 

Relevant articles and documents

Methyl 3,3,3-trifluoropyruvate hemiaminals: Stability and transaminations

Hemiaminals of methyl 3,3,3-trifluoropyruvate with aromatic amines, benzylic monoamines and diamines were prepared and their interconversions studied using NMR spectrometry. In solution, benzylic hemiaminals were found to be stable in contrast to aromatic hemiaminals, which, in turn, were stable in the solid state.

Preparation of new trifluoromethyl substituted Tri- and tetracyclic heterocycles with peganin skeleton from a methyl 3,3,3-trifluoropyruvate/2-aminobenzylamine adduct

Addition of 2-aminobenzylamino to methyl trifluoropyruvate afforded methyl 2-((2-aminobenzyl)amino)-3,3,3-trifluoro-2-hydroxypropionate, which reacted with various ketones to give new fluorinated tricyclic and tetracyclic heterocycles with the skeleton of