119870-20-1

Basic information

• Product Name: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)
• Synonyms: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE);2-benzyloxy-1,3-propanediol 1-(toluene-4-sulfonate);2-Benzyl-sn-glycerol 3-tosylate, (R)-2-Benzyloxy-3-(p-toluenesulfonyloxy)-1-propanol;(R)-2-Benzyloxy-3-(p-toluenesulfonyloxy)-1-propanol;2-Benzyl-sn-glycerol 3-tosylate
• CAS NO: 119870-20-1
• Molecular Formula: C₁₇H₂₀O₅S
• Molecular Weight: 336.4027
• Mol File: 119870-20-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 40-43 °C
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)(119870-20-1)
• EPA Substance Registry System: (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE)(119870-20-1)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 119870-20-1(Hazardous Substances Data)

Usage

General Description

(R)-2-Benzyloxy-1,3-propanediol 1-(p-toluenesulfonate) is a chemical compound that consists of a propanediol molecule with a benzyloxy group attached to one of the carbon atoms. It is commonly used as a reagent in organic chemistry reactions, where the p-toluenesulfonate group can act as a leaving group in substitution or elimination reactions. (R)-2-BENZYLOXY-1,3-PROPANEDIOL 1- (P-TOLUENESULFONATE) is often used in the synthesis of pharmaceuticals and other organic compounds due to its versatile reactivity and ability to participate in a variety of chemical transformations. Additionally, it can also be used as a chiral building block for the construction of complex molecules with specific stereochemistry.

Upstream product

• 14690-00-7 2-O-benzylglycerol 
• 98-59-9 p-toluenesulfonyl chloride 
• 109429-01-8 (S)-2-(benzyloxy)-3-hydroxypropyl acetate 
• 128223-59-6 (R)-1-O-Acetyl-2-O-benzyl-3-tosylglycerol 

Downstream Products

• 146797-75-3 (R)-2-O-benzyl-3-O-tetrahydropyranyl-1-O-tosylglycerol 
• 41274-09-3 (R)-3-tosyloxy-1,2-propanediol 
• 119870-22-3 (S)-2-benzyloxy-3-isopropylamino-1-propanol 
• 146923-48-0 (S)-2-O-benzyl-3-O-hexadecyl-1-O-tetrahydropyranylglycerol 
• 147200-16-6 (R)-2-Benzyloxy-3-butoxy-propan-1-ol 
• 147118-43-2 2-((S)-2-Benzyloxy-3-butoxy-propoxy)-tetrahydro-pyran 
• 147118-44-3 (S)-2-O-benzyl-1-O-butyl-3-O-tosylglycerol 
• 119870-21-2 ((S)-2-Benzyloxy-3-chloro-propyl)-isopropyl-amine 
• 67800-64-0 1-O-tosyl-2,3-O-methylidene-D-glycerol 
• 127559-70-0 Acetic acid (R)-2-acetoxymethoxy-3-(toluene-4-sulfonyloxy)-propyl ester 
• 129453-80-1 Acetic acid (R)-1-acetoxymethoxymethyl-2-(toluene-4-sulfonyloxy)-ethyl ester 
• 127559-71-1 Acetic acid (R)-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethoxy)-3-(toluene-4-sulfonyloxy)-propyl ester 

Relevant articles and documents

Synthesis of optically active lipopeptide analogs from the outer membrane of Escherichia coli

The synthesis of optically active lipopeptide derivatives has been accomplished by the use of chiral glycerol derivatives. Lipopeptide derivatives with (R)-glycerol moieties showed higher mitogenic activities than those with the (S)-configuration. N-2,2,2-Trichloroethoxycarbonyl lipopeptide derivatives increased mitogenic activity.

Synthesis of biologically active acycloazt derivatives and related compounds

The synthesis of optically active acyclic analogues of 3'-azido-3'-deoxythymidine, which lack only the 2'-CH2 of the sugar, is described. The synthesis of some nucleoside analogues that contain the N-acetyl-D-neuraminic acid moiety is also described.