1198760-89-2Relevant academic research and scientific papers
A stereoselective approach to nucleosides and 4′-thioanalogues from acyclic precursors
Chapdelaine, Daniel,Cardinal-David, Benoit,Prevost, Michel,Gagnon, Marc,Thumin, Isabelle,Guindon, Yvan
supporting information; experimental part, p. 17242 - 17245 (2010/03/25)
D- and L-nucleosides and analogues thereof, including the 4′-thionucleoside series, are one of the most important biological and pharmaceutically active classes of compounds. A novel approach to their synthesis from chiral acyclic thioaminal, bearing the nucleobase, is described.
