1198783-33-3Relevant academic research and scientific papers
Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation
Parlow, John J.,Burney, Mary W.,Case, Brenda L.,Girard, Thomas J.,Hall, Kerri A.,Hiebsch, Ronald R.,Huff, Rita M.,Lachance, Rhonda M.,Mischke, Deborah A.,Rapp, Stephen R.,Woerndle, Rhonda S.,Ennis, Michael D.
scheme or table, p. 6148 - 6156 (2010/07/02)
Piperazinyl-glutamate-pyrimidines were prepared with oxygen, nitrogen, and sulfur substitution at the 4-position of the pyrimidine leading to highly potent P2Y12 antagonists. In particular, 4-substituted piperidine-4-pyrimidines provided compou
