119879-64-0

Basic information

• Product Name: 23,25-dimethylergosta-5,24(28)-dien-3β-ol
• CAS NO: 119879-64-0
• Molecular Weight: 426.726
• Mol File: 119879-64-0.mol

Chemical Properties

• CAS DataBase Reference: 23,25-dimethylergosta-5,24(28)-dien-3β-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 23,25-dimethylergosta-5,24(28)-dien-3β-ol(119879-64-0)
• EPA Substance Registry System: 23,25-dimethylergosta-5,24(28)-dien-3β-ol(119879-64-0)

Safety Data

• Hazardous Substances Data: 119879-64-0(Hazardous Substances Data)

Upstream product

• 39761-57-4 (E)-3,4,4-trimethyl-2-pentene 
• 51231-25-5 6β-methoxy-3α,5-cyclo-5α-23,24-dinorcholan-22-iodide 

Relevant articles and documents

Scope and Regiochemical Control of the Allylpotassium Reaction in the Synthesis of Sterols with Unsaturated Side Chains

Allylpotassium derivatives were prepared from a variety of olefins by using Schlosser's base (BuLi/KOt-Bu).Reaction with (20S)-20-(iodomethyl)pregnane i-methyl ether (1) followed by deprotection gave in high yields a wide variety of Δ24 and Δ24(28) sterols, including the naturally occuring desmosterol (37), fucosterol (33), 24(E)-propylidenecholesterol (35), 24-methylenecholesterol (3), dehydroaplysterol (10), 25-methyl-24-methylenecholesterol (11), mutasterol (12), and 25-methylxestosterol (13).Control of the regiochemistry of unsymmetrical allylmetals was achieved through the addition of Li2CuCl3.Rules concerning the high regioselectivities and stereoselectivities are discussed.