119895-70-4

Basic information

• Product Name: 2,2,3,3-TETRAFLUORO-5-AMINO-1,4-BENZODIOXENE
• Synonyms: 5-AMINO-2,2,3,3-TETRAFLUORO-1,4-BENZODIOXAN;5-AMINO-2,2,3,3-TETRAFLUORO-1,4-BENZODIOXENE;2,2,3,3-TETRAFLUORO-5-AMINO-1,4-BENZODIOXENE;2,2,3,3-TETRAFLUORO-5-AMINOBENZODIOXENE;5-Amino-2,2,3,3-tetrafluoro-1,4-benzodioxane;2,3-[(Tetrafluoroethylene)dioxy]aniline;2,3-[(Tetrafuoroethylene)dioxy]aniline;5-Amino-2,2,3,3-tetrafluoro-1,4-benzodioxene 98%
• CAS NO: 119895-70-4
• Molecular Formula: C₈H₅F₄NO₂
• Molecular Weight: 223.12
• Mol File: 119895-70-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 221.2°Cat760mmHg
• Flash Point: 87.6°C
• Appearance: /
• Density: 1.57g/cm³
• Storage Temp.: 2-8°C
• PKA: 2.68±0.60(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2,2,3,3-TETRAFLUORO-5-AMINO-1,4-BENZODIOXENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,3,3-TETRAFLUORO-5-AMINO-1,4-BENZODIOXENE(119895-70-4)
• EPA Substance Registry System: 2,2,3,3-TETRAFLUORO-5-AMINO-1,4-BENZODIOXENE(119895-70-4)

Safety Data

• Hazard Codes: T
• Statements: 20/21/22-36/37/38
• Safety Statements: 36/37/39-45
• Hazardous Substances Data: 119895-70-4(Hazardous Substances Data)

Usage

Uses

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine can be used to synthesize derivatives of 2-(3,4,5-trimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine as B-RAF inhibitors.

Upstream product

• 149045-83-0 6,7-Dibromo-5-nitro-2,2,3,3-tetrafluoro-benzo(1.4)-dioxane 

Relevant articles and documents

Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates

According to the invention, a new process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes of the formula (I) STR1 in which n represents an integer 1 or 2, has been found, in which fluorine-substituted nitrohalogeno-benzodioxoles and -benzodioxanes, which are likewise new, are hydrogenated. The novel intermediates are obtained from fluorine-substituted benzodioxoles and benzodioxanes by halogenation and subsequent nitration. The amino compounds are important starting materials for highly active biocides.