119906-35-3Relevant academic research and scientific papers
5′-Homoaristeromycin. Synthesis and antiviral activity against orthopox viruses
Yang, Minmin,Schneller, Stewart W.
, p. 149 - 151 (2005)
An efficient synthesis of 5′-homoaristeromycin has been developed. This permitted an extensive antiviral analysis, which found potent activity toward vaccinia, cowpox, and monkeypox viruses. For comparative purposes, 5′-homoadenosine was made available by a newly designed route and found to be inactive.
SYNTHESIS OF CARBOCYCLIC NUCLEOSIDES: PREPARATION OF (-)-5'-HOMOARISTEROMYCIN AND ANALOGUES
Jones, Martin F.,Roberts, Stanley M.
, p. 2927 - 2932 (2007/10/02)
Optically pure 5'-homoaristeromycin has been prepared from (L)-ribonolactone using an intramolecular radical cyclisation process to form the five-membered carbocyclic ring with subsequent displacement of a triflate group using a substituted purine to intr
