119908-54-2Relevant academic research and scientific papers
Axial Chirality by Asymmetric Induction. Diastereomeric Allene Formation via Silicon as a Chiral Auxiliary
Stang, Peter J.,Learned, Alan E.
, p. 1779 - 1781 (1989)
Interaction of alkenylidenecarbenes, RCH=C=C:, R = CH3 and t-Bu, with chiral α-NpPhMeSi*H results in chiral allenes with a 3.5 +/- 0.5percent and 10.5 +/- 0.5percent diastereomeric excess, respectively.Hence the transfer of central chirality to axial chirality, via silicon as a chiral auxiliary, has been established.These results are discussed, and a transmission state is proposed.
