119930-74-4Relevant academic research and scientific papers
NOVEL VASCULAR LEAKAGEAGE INHIBITOR
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Paragraph 0131, (2015/01/07)
The present disclosure relates to a novel vascular leakage inhibitor. The novel vascular leakage inhibitor of the present invention inhibits the apoptosis of vascular endothelial cells, inhibits the formation of actin stress fibers induced by VEGF, and enhances the cortical actin ring structure, thereby inhibiting vascular leakage. Accordingly, the vascular leakage inhibitor of the present invention can prevent or treat various diseases caused by vascular leakage. Since the vascular leakage inhibitor of the present invention is synthesized from commercially available or easily synthesizable pregnenolones, it has remarkably superior feasibility of commercial synthesis.
Nucleophilic Aromatic Substitution on Tricarbonyl(halogenoarene)chromium Complexes: A New Synthesis of O-Arylhydroxylamines
Baldoli, Clara,Buttero, Paola Del,Licandro, Emanuela,Maiorana, Stefano
, p. 344 - 345 (2007/10/02)
A series of O-arylhydroxylamines 4 have been synthesized under mild conditions and in good yields by the reaction of tricarbonyl(halogenoarene)chromium complexes 1 with N-(tert-butyloxycarbonyl)hydroxylamine (tert-butyl N-hydroxycarbamate), followed by decomplexation and acidic hydrolysis of the tert-butyl N-(aryloxy)carbamates 3.
