119934-21-3

Basic information

• Product Name: ethyl 2-(4-bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
• Synonyms: ethyl 2-(4-bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
• CAS NO: 119934-21-3
• Molecular Formula: C₁₈H₁₈BrNO₃S
• Molecular Weight: 408.30942
• Mol File: 119934-21-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 485.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.483±0.06 g/cm3(Predicted)
• PKA: 12.35±0.20(Predicted)
• CAS DataBase Reference: ethyl 2-(4-bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate(119934-21-3)
• EPA Substance Registry System: ethyl 2-(4-bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate(119934-21-3)

Safety Data

• Hazardous Substances Data: 119934-21-3(Hazardous Substances Data)

Upstream product

• 586-76-5 4-Bromobenzoic acid 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 586-75-4 4-chlorobenzoyl chloride 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 119260-84-3 5-(4-Brom-phenyl)-2,3,8,9,10,11-hexahydro-benzothieno<3,2-e>imidazo<1,2-c>pyrimidinhydrochlorid 
• 119260-90-1 2-(4-Bromo-phenyl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d][1,3]thiazine-4-thione 

Relevant articles and documents

Preparation method and application of tetrahydrobenzothiophene compound and pharmaceutical composition

The invention belongs to the field of medicines, and particularly relates to a tetrahydrobenzothiophene compound as well as a pharmaceutical composition and a preparation method and application thereof. The tetrahydrobenzothiophene compound is a compound I as shown I. In-flight R1 And R2 The C1 -4 is a saturated/unsaturated hydrocarbon group. - OCH3 , OCH2 CH3 Phenyl, substituted phenyl, NO2 One - COR of - OH - F, Cl - Br. I - H R1 AND R2 Or different. R3 It is-F. - Cl, Br, I, OH, Amino, C1 -4 saturated/unsaturated hydrocarbon group, OCH3 , OCH2 CH3 , H, Wherein one of them is, n ≥ 5, n Being an integer. The compound effectively inhibits salmonella by inhibiting the synthesis of ATP-dependent transporter in the lipopolysaccharide synthesis pathway. Aeruginosa, escherichia coli and staphylococcus aureus.