119943-83-8Relevant articles and documents
Enzyme-catalyzed Asymmetric Hydrolysis of meso-Substrate. The Facile Synthesis of Both Enantiomers of cis-2,5-Disubstituted Tetrahydrofuran Derivatives
Naemura, Koichiro,Takahashi, Nobuo,Chikamatsu, Hiroaki
, p. 1717 - 1720 (2007/10/02)
The enzyme-catalyzed asymmetric hydrolysis of the meso-diesters derived from cis-2,5-bis(hydroxymethyl)tetrahydrofuran in presence of PLE, PPL, and CCL afforded the optically active half-esters.The both enantiomers of cis-5-(hydroxymethyl)tetrahydrofuran-2-carboxylic acid with high optical purity were prepared from the half-esters.