119945-34-5

Upstream product

• 1458-98-6 2-methyl-3-bromo-1-propene 
• 119909-62-5 (1R,2R)-cyclopentane-1,2-dicarboxylic acid mono-(+)-menthyl ester 
• 96149-02-9 (+)-Dimenthyl (1R,2R)-cyclopentane-1,2-dicarboxylate 

Downstream Products

• 119909-65-8 (3aS,7aR)-5-Methyl-7-oxo-1,2,3,4,7,7a-hexahydro-indene-3a-carboxylic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 119909-63-6 (1S,2R)-1-(2-Methyl-allyl)-cyclopentane-1,2-dicarboxylic acid 1-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 
• 119909-64-7 (1S,2R)-1-(2-Methyl-allyl)-cyclopentane-1,2-dicarboxylic acid 1-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 2-methyl ester 
• 119945-35-6 (1R,2R)-1-(2-Methyl-allyl)-cyclopentane-1,2-dicarboxylic acid 1-((1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl) ester 2-methyl ester 
• 147649-21-6 (3aR,7aS)-5-Methyl-7-oxo-1,2,3,4,7,7a-hexahydro-indene-3a-carboxylic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 

Relevant academic research and scientific papers

Total synthesis of natural (-)-ptaquilosin, the aglycon of a potent bracken carcinogen ptaquiloside, and the (+)-enantiomer and their DNA cleaving activities

The total synthesis of natural (-)-ptaquilosin (2) the aglycon of a potent carcinogen ptaquiloside (1) from bracken fern and its (+)-enantiomer (2) has been achieved starting with (+)-dimenthyl (1,2R)-cyclopentane-1,2-dicarboxylate. The synthesis proceeds

Factors that cause contrasteric alkylation of a cyclopentane-1,2-dicarboxylic acid monoester

The stereochemical outcome in the alkylation of the enolate generated from a cyclopentane-1,2-dicarboxylic acid monoester is described. The alkylation of the Li enolate with an ankylating reagent having a hard leaving group such as Cl gave a contrasteric