1199557-04-4

Basic information

• Product Name: CarbaMic acid, N-(6-chloro-2-forMyl-3-pyridinyl)-, 1,1-diMethylethyl ester
• Synonyms: tert-butyl 6-chloro-2-forMylpyridin-3-ylcarbaMate;3-(Boc-aMino)-6-chloro-2-forMylpyridine;tert-butyl N-(6-chloro-2-formylpyridin-3-yl)carbamate;CarbaMic acid, N-(6-chloro-2-forMyl-3-pyridinyl)-, 1,1-diMethylethyl ester;3-(Boc-aMino)-6-chloro-2-...
• CAS NO: 1199557-04-4
• Molecular Formula: C₁₁H₁₃ClN₂O₃
• Molecular Weight: 257
• Mol File: 1199557-04-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 319.9±42.0 °C(Predicted)
• Appearance: /
• Density: 1.314±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.55±0.70(Predicted)
• CAS DataBase Reference: CarbaMic acid, N-(6-chloro-2-forMyl-3-pyridinyl)-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: CarbaMic acid, N-(6-chloro-2-forMyl-3-pyridinyl)-, 1,1-diMethylethyl ester(1199557-04-4)
• EPA Substance Registry System: CarbaMic acid, N-(6-chloro-2-forMyl-3-pyridinyl)-, 1,1-diMethylethyl ester(1199557-04-4)

Safety Data

• Hazardous Substances Data: 1199557-04-4(Hazardous Substances Data)

Usage

General Description

Carbamic acid, N-(6-chloro-2-formyl-3-pyridinyl)-, 1,1-dimethylethyl ester is a chemical compound with the molecular formula C12H13ClN2O3. It is known for its role in chemical synthesis and research, specifically within the pharmaceutical industry. Its chemical structure includes a carbamic acid group, a pyridine ring, a formyl group and a dimethylethyl ester group. Despite its complex nomenclature, it is mainly used as a reagent or building block in the production of more complex compounds. Details about its safety, toxicity, and environmental effects might be limited due to its specific and technical use.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1227958-32-8 tert-butyl (2-bromo-6-chloropyridin-3-yl)carbamate 
• 68-12-2 N,N-dimethyl-formamide 
• 1050501-88-6 2-bromo-6-chloro-pyridin-3-amine 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 

Downstream Products

• 1199556-79-0 6-hydrazinyl-3-phenyl-1,5-naphthyridin-2(1H)-one 
• 1199557-01-1 1-(difluoromethyl)-8-phenyl[1,2,4]triazolo[4,3-a][1,5]-naphthyridin-7(6H)-one 
• 1199557-02-2 7-chloro-1-(difluoromethyl)-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridine 
• 1199556-83-6 2-{trans-3-cyclopropyl-1-[4-(1-ethyl-8-phenyl[1,2,4]triazolo[4,3-a]-1,5-naphthyridin-7-yl)phenyl]-3-hydroxycyclobutyl}-1H-isoindole-1,3(2H)-dione 
• 1199557-03-3 2-(trans-1-{4-[1-(difluoromethyl)-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridin-7-yl]phenyl}-3-hydroxy-3-methylcyclobutyl)-1H-isoindole-1,3(2H)-dione 
• 1199556-23-4 trans-3-amino-1-cyclopropyl-3-[4-(1-ethyl-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridin-7-yl)phenyl]cyclobutanol 
• 1199556-40-5 trans-3-amino-3-{4-[1-(difluoromethyl)-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridin-7-yl]phenyl}-1-methylcyclobutanol 
• 1199556-80-3 N'-(6-oxo-7-phenyl-5,6-dihydro-1,5-naphthyridin-2-yl)propanohydrazide 
• 1199556-82-5 7-chloro-1-ethyl-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridine 
• 1199556-81-4 1-ethyl-8-phenyl-[1,2,4]triazolo[4,3-a]-1,5-naphthyridin-7(6H)-one 
• 1199556-61-0 tert-butyl {1-[4-(6-chloro-3-phenyl-1,5-naphthyridin-2-yl)phenyl]cyclobutyl}carbamate 
• 1199556-78-9 6-chloro-3-phenyl-1,5-naphthyridin-2(1H)-one 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE

The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.