1199794-65-4

Basic information

• Product Name: N-benzyloxycarbonyl-3-methyl-4-methoxy-L-phenylalanine methyl ester
• Synonyms: N-benzyloxycarbonyl-3-methyl-4-methoxy-L-phenylalanine methyl ester
• CAS NO: 1199794-65-4
• Molecular Weight: 357.406
• Mol File: 1199794-65-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-benzyloxycarbonyl-3-methyl-4-methoxy-L-phenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxycarbonyl-3-methyl-4-methoxy-L-phenylalanine methyl ester(1199794-65-4)
• EPA Substance Registry System: N-benzyloxycarbonyl-3-methyl-4-methoxy-L-phenylalanine methyl ester(1199794-65-4)

Safety Data

• Hazardous Substances Data: 1199794-65-4(Hazardous Substances Data)

Upstream product

• 1219720-74-7 N-Cbz-3-methyl-L-tyrosine 
• 77-78-1 dimethyl sulfate 
• 1219720-76-9 C₂₁H₂₅NO₆ 
• 1219720-75-8 N-Cbz-3-hydroxymethyl-4-methoxy-L-phenylalanine methyl ester 
• 50-00-0 formaldehyd 
• 1164-16-5 Z-L-Tyr-OH 

Downstream Products

• 1199794-66-5 N-benzyloxycarbonyl-3-formyl-4-methoxy-5-methyl-L-phenylalanine methyl ester 
• 1150635-61-2 N-benzyloxycarbonyl-3-hydroxy-4-methoxy-5-methyl-L-phenylalaninol 

Relevant articles and documents

A Scalable Total Synthesis of the Antitumor Agents Et-743 and Lurbinectedin

An efficient and scalable approach is described for the total synthesis of the marine natural product Et-743 and its derivative lubinectedin, which are valuable antitumor compounds. The method delivers 1.6 % overall yield in 26 total steps from Cbz-protected (S)-tyrosine. It features the use of a common advanced intermediate to create the right and left parts of these compounds, and a light-mediated remote C?H bond activation to assemble a benzo[1,3]dioxole-containing intermediate.