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1199795-06-6

benzyl 4-(3-(naphthalen-1-ylsulfonyl)-1H-indazol-5-yl)piperazine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1199795-06-6 Structure

  • Basic information

    1. Product Name: benzyl 4-(3-(naphthalen-1-ylsulfonyl)-1H-indazol-5-yl)piperazine-1-carboxylate
    2. Synonyms: benzyl 4-(3-(naphthalen-1-ylsulfonyl)-1H-indazol-5-yl)piperazine-1-carboxylate
    3. CAS NO:1199795-06-6
    4. Molecular Formula:
    5. Molecular Weight: 526.616
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1199795-06-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: benzyl 4-(3-(naphthalen-1-ylsulfonyl)-1H-indazol-5-yl)piperazine-1-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: benzyl 4-(3-(naphthalen-1-ylsulfonyl)-1H-indazol-5-yl)piperazine-1-carboxylate(1199795-06-6)
    11. EPA Substance Registry System: benzyl 4-(3-(naphthalen-1-ylsulfonyl)-1H-indazol-5-yl)piperazine-1-carboxylate(1199795-06-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1199795-06-6(Hazardous Substances Data)

1199795-06-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1199795-06-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,9,7,9 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1199795-06:
(9*1)+(8*1)+(7*9)+(6*9)+(5*7)+(4*9)+(3*5)+(2*0)+(1*6)=226
226 % 10 = 6
So 1199795-06-6 is a valid CAS Registry Number.

1199795-06-6Downstream Products

1199795-06-6Relevant articles and documents

5-piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists

Liu, Kevin G.,Robichaud, Albert J.,Bernotas, Ronald C.,Yan, Yinfa,Lo, Jennifer R.,Zhang, Mei-Yi,Hughes, Zoe A.,Huselton, Christine,Zhang, Guo Ming,Zhang, Jean Y.,Kowal, Dianne M.,Smith, Deborah L.,Schechter, Lee E.,Comery, Thomas A.

experimental part, p. 7639 - 7646 (2011/02/21)

As part of our efforts to develop agents for CNS diseases, we have been focused on the 5-HT6 receptor in order to identify potent and selective ligands for cognitive enhancement. Herein we report the identification of a novel series of 5-piperazinyl-3-sulfonylindazoles as potent and selective 5-HT6 antagonists. The synthesis, SAR, and pharmacokinetic and pharmacological activities of some of the compounds including 3-(naphthalen-1-ylsulfonyl)-5-(piperazin-1-yl)-1H-indazole (WAY-255315 or SAM-315) will be described.

1-SUBSTITUTED-3-(NAPHTHALEN-1-YLSULFONYL)-5-(PIPERAZIN-1-YL)-1H-INDAZOLE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS

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Page/Page column 13, (2009/12/28)

The disclosure is directed to compounds of Formula I: processes for their preparation, treatment of central nervous system (CNS) disorders and methods for the modulation of 5HT6 activity.

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