119992-81-3

Usage

Uses

Used in Organic Synthesis:
[(1S)-1-methylbutyl] methanesulfonate is used as a reagent in organic synthesis for its mild, non-nucleophilic alkylating properties. It is particularly useful in chemical reactions where a mild alkylating agent is required.
Used as a Solvent:
[(1S)-1-methylbutyl] methanesulfonate is also employed as a solvent for organic compounds due to its solubility in organic solvents.
Used in Pharmaceutical Industry:
[(1S)-1-methylbutyl] methanesulfonate may have potential applications in the pharmaceutical industry, where its mild alkylating properties can be utilized for specific chemical reactions in drug development.
Used in Agrochemicals:
Similarly, in the agrochemicals industry, [(1S)-1-methylbutyl] methanesulfonate could be used for its alkylating properties in the synthesis of various agrochemical products.

Upstream product

• 26184-62-3 (S)-2-pentanol 

Relevant academic research and scientific papers

Method for the Production of Optically Active 3-Alkyl Carboxylic Acids and the Intermediate Products Thereof

An enantioselective method for producing optically active 3-alkyl carboxylic acids comprises transforming an optically active secondary alcohol into an optically active, activated compound by introducing a leaving group; reacting the activated compound with a malonic acid derivative to obtain an optically active, alkylated malonic acid compound, the reaction taking place exclusively in ether and/or carboxylic acid ester solvents and one or more aprotic polar solvents or alcohols as a cosolvent in a maximum proportion of 30 volume percent of total solvent, wherein the added cosolvent is not hexamethyl phosphoric acid triamide; the malonic acid compound is hydrolyzed if necessary to obtain the corresponding acid; and the corresponding acid is decarboxylated.

METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 3-ALKYL CARBOXYLIC ACIDS AND THE INTERMEDIATE PRODUCTS THEREOF

The invention relates to an enantioselective method for producing optically active 3-alkyl carboxylic acids, comprising the following steps: A) an optically active secondary alcohol is transformed into an optically active, activated compound by introducing a terminal group; B) the activated compound is reacted with a malonic acid derivative so as to obtain an optically active, alkylated malonic acid compound, the reaction taking place exclusively in the presence of one or several solvents selected among the class of ethers or carboxylic acid ethers and one or several aprotically polar solvents or alcohols being optionally added as a cosolvent at a maximum proportion of 30 percent of the total added solvent volume, provided that the added cosolvent is not hexamethyl phosphoric acid triamide; C) the malonic acid compound is saponified if necessary to obtain the corresponding acid; and D) the corresponding acid is finally decarboxylated.