1199947-72-2Relevant academic research and scientific papers
Synthesis of 1-substituted benzimidazoles from o-bromophenyl isocyanide and amines
Lygin, Alexander V.,De Meijere, Armin
, p. 5138 - 5141 (2009)
o-Bromophenyl isocyanide (1-Br) reacts with various primary amines under Cu1 catalysis to afford 1 -substituted benzimidazoles 4 in moderate to good yields (38-70%, 13 examples). Analogously, 2-b:romo-3-isocyanothiophene (6) furnishes-substituted 3H-thieno[2,3-d]imidazoles 7 (44-49%, 3 examples).
