1200114-72-2Relevant academic research and scientific papers
Regioselective palladium(0)-catalyzed cross-coupling reactions and metal-halide exchange reactions of tetrabromothiophene: Optimization, scope and limitations
Tung, Dang Thanh,Tuan, Dang Thanh,Rasool, Nasir,Villinger, Alexander,Reinke, Helmut,Fischer, Christine,Langer, Peter
experimental part, p. 1595 - 1609 (2011/02/25)
The Suzuki reaction of tetrabromothiophene with arylboronic acids provides a regioselective approach to various 5-aryl-2,3,4-tribromothiophenes, symmetrical 2,5-diaryl-3,4-dibromothiophenes, and tetraarylthiophenes. Unsymmetrical 2,5-diaryl-3,4-dibromo thiophenes are prepared by Suzuki reaction of 5-aryl-2,3,4-tribromothiophenes. Tetraarylthiophenes containing two different types of aryl groups are obtained by Suzuki reactions of 2,5-diaryl-3,4- dibromothiophenes. During the optimization of the conditions of each individual reaction, the solvent, the catalyst and the temperature play an important role. In several cases, classical conditions.
