1200130-72-8

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-2-Methyl-1-(phenylsulfonyl)-, Methyl ester
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-2-Methyl-1-(phenylsulfonyl)-, Methyl ester;SGWOSMWMDSKWPY-UHFFFAOYSA-N
• CAS NO: 1200130-72-8
• Molecular Formula: C₁₆H₁₃BrN₂O₄S
• Molecular Weight: 409.25442
• Mol File: 1200130-72-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-2-Methyl-1-(phenylsulfonyl)-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-2-Methyl-1-(phenylsulfonyl)-, Methyl ester(1200130-72-8)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-2-Methyl-1-(phenylsulfonyl)-, Methyl ester(1200130-72-8)

Safety Data

• Hazardous Substances Data: 1200130-72-8(Hazardous Substances Data)

Usage

Molecular Weight

384.22 g/mol The molecular weight is the mass of one mole of the compound.

Structure

1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-broMo-2-Methyl-1-(phenylsulfonyl)The structure describes the arrangement of atoms in the molecule.

Class

Pyrrolopyridine The class represents the group of organic compounds to which the molecule belongs.

Derivative

Methyl ester The derivative indicates that the compound is a modified form of the parent compound.

Potential Applications

Medicinal chemistry and pharmaceutical research The compound has potential applications in these fields due to its interesting biological activities and its use as a building block for the synthesis of new chemical entities.

Safety Precautions

Handle with care and in accordance with safety guidelines The compound may have potential hazards and risks associated with its handling and use.

Upstream product

• 1200130-71-7 1-benzenesulfonyl-5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester 
• 74-88-4 methyl iodide 
• 381233-96-1 2-amino-3-iodo-5-bromopyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 1228551-75-4 5-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester 
• 98-09-9 benzenesulfonyl chloride 
• 1111638-02-8 5-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine 
• 1312755-43-3 5-bromo-3-(prop-1-yn-1-yl)pyridin-2-amine 
• 872619-43-7 5-bromo-1H-pyrrole[2,3-b]pyrimidine-3-carboxylic acid methyl ester 

Downstream Products

• 1200130-73-9 1-benzenesulfonyl-5-bromo-2-bromomethyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester 
• 1200130-70-6 9-benzenesulfonyl-5-hydroxy-9H-dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile 
• 1200130-74-0 1-benzenesulfonyl-5-bromo-2-{[cyanomethyl-(toluene-4-sulfonyl)amino]methyl}-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester 
• 1200130-75-1 9-benzenesulfonyl-3-bromo-5-hydroxy-9H-dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile 
• 1200132-31-5 9-benzenesulfonyl-3-bromo-5-(piperidin-4-yloxy)-9H-dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile 
• 1312755-44-4 9-benzenesulfonyl-3-bromo-5-chloro-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 
• 1312756-21-0 4-(9-benzenesulfonyl-3-bromo-6-cyano-9H-dipyrido[2,3-b;4',3'-d]pyrrol-5-yloxy)piperidine-1-carboxylic acid tert-butyl ester 
• 1312756-22-1 9-benzenesulfonyl-3-bromo-5-[1-(2,2-difluoroethyl)-piperidin-4-yloxy]-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 
• 1312756-23-2 9-benzenesulfonyl-5-[1-(2,2-difluoroethyl)-piperidin-4-yloxy]-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 
• 1312756-24-3 9-benzenesulfonyl-3-bromo-5-[1-(2-methanesulfonylethyl)-piperidin-4-yloxy]-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 
• 1312756-25-4 9-benzenesulfonyl-5-[1-(2-methanesulfonylethyl)-piperidin-4-yloxy]-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 
• 1312756-26-5 9-benzenesulfonyl-3-bromo-5-{1-[2-(tetrahydropyran-2-yloxy)-ethyl]-piperidin-4-yloxy}-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 
• 1312756-27-6 9-benzenesulfonyl-3-bromo-5-[1-(2-hydroxyethyl)-piperidin-4-yloxy]-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 
• 1312756-28-7 9-benzenesulfonyl-5-[1-(2-hydroxyethyl)-piperidin-4-yloxy]-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile 

Relevant articles and documents

1, 7 - DIAZACARBAZOLES AND THEIR USE IN THE TREATMENT OF CANCER

The invention relates to 1, 7-diazacarbazole compounds of Formula (I), (I-a) and (I-b) which are useful as kinase inhibitors, more specifically useful as checkpoint kinase 1 (chk 1) inhibitors, thus useful as cancer therapeutics. The invention also relates to compositions, more specifically pharmaceutical compositions comprising these compounds and methods of using the same to treat various forms of cancer and hyperproliferative disorders, as well as methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.