1200440-07-8Relevant academic research and scientific papers
Modified Julia-Kocienski Reagents for a Stereoselective Introduction of Trisubstituted Double Bonds: A Formal Total Synthesis of Limazepine e and Barmumycin
Sakaine, Guna,Smits, Gints
, p. 5323 - 5330 (2018)
A formal total synthesis of pyrrolo[1,4]benzodiazepine anticancer antibiotic family member limazepine E is described. The synthesis features a stereoselective introduction of a trisubstituted double bond using novel sterically demanding Julia-Kocienski re
THERAPEUTIC COMPOUNDS AND USES THEREOF
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Page/Page column 51; 81, (2019/07/17)
The present invention relates to compounds useful in the modulation of ion channel activity in cells. The invention also relates to use of these compounds in the treatment of pain, and pharmaceutical compositions containing these compounds and methods for their preparation.
TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS
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Page/Page column 26, (2011/04/25)
The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R1, R2 and R3 are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.
TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS
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Page/Page column 62, (2010/01/07)
The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R1, R2 and R3 are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.
