1200462-96-9

Basic information

• Product Name: 3'-O-bis-(tert-butylsimethylsilyl)-5-[(S)-1-(2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-2'-deoxyuridine
• CAS NO: 1200462-96-9
• Molecular Weight: 563.723
• Mol File: 1200462-96-9.mol

Chemical Properties

• CAS DataBase Reference: 3'-O-bis-(tert-butylsimethylsilyl)-5-[(S)-1-(2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-2'-deoxyuridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-bis-(tert-butylsimethylsilyl)-5-[(S)-1-(2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-2'-deoxyuridine(1200462-96-9)
• EPA Substance Registry System: 3'-O-bis-(tert-butylsimethylsilyl)-5-[(S)-1-(2-nitrophenyl)-2,2-dimethyl-propyloxy]methyl-2'-deoxyuridine(1200462-96-9)

Safety Data

• Hazardous Substances Data: 1200462-96-9(Hazardous Substances Data)

Upstream product

• 1200463-02-0 (S)-1-(2-nitrophenyl)-2,2-dimethyl-1-propanol 
• 1028383-90-5 N³-tert-butyloxycarbonyl-5-bromomethyl-3',5'-bis-O-tert-butyldimethylsilyl-2'-deoxyuridine 

Relevant articles and documents

Stereochemistry of benzylic carbon substitution coupled with ring modification of 2-nitrobenzyl groups as key determinants for fast-cleaving reversible terminators

A complete set of 2-nitrobenzyl-modified reversible terminators have been developed, which upon exposure to UV light generate natural hydroxymethyl nucleotides (see scheme). The combination of a stereospecific (S)-tert-butyl group (R) at the benzylic carb