1200508-86-6

Basic information

• Product Name: 8-Oxo-4-aza-tricyclo[5.2.1.02,6]decane-4-carboxylic acid tert-butyl ester
• Synonyms: 8-Oxo-4-aza-tricyclo[5.2.1.02,6]decane-4-carboxylic acid tert-butyl ester
• CAS NO: 1200508-86-6
• Molecular Formula: C14H21NO3
• Molecular Weight: 251
• Mol File: 1200508-86-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-Oxo-4-aza-tricyclo[5.2.1.02,6]decane-4-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Oxo-4-aza-tricyclo[5.2.1.02,6]decane-4-carboxylic acid tert-butyl ester(1200508-86-6)
• EPA Substance Registry System: 8-Oxo-4-aza-tricyclo[5.2.1.02,6]decane-4-carboxylic acid tert-butyl ester(1200508-86-6)

Safety Data

• Hazardous Substances Data: 1200508-86-6(Hazardous Substances Data)

Relevant articles and documents

Enantioselective synthesis of tricyclic amino acid derivatives based on a rigid 4-azatricyclo[5.2.1.02,6]decane skeleton

An enantioselective route to four tricyclic amino acids and N-tosylamides, composed of a central norbornane framework with a 2-endo,3-endo-annelated pyrrolidine ring and a 5-endo-C1 or -C2 side chain, has been developed. A key intermediate was the chiral, N-Boc-protected ketone (1R,2S,6S,7R)-4-azatricyclo[5.2.1.02,6]decan-8-one, available from inexpensive endo-carbic anhydride in five steps and 47% yield. The rigid scaffold makes these amino acid derivatives promising candidates for β-turn-inducing building blocks in peptidomimetics and for chiral auxiliaries in asymmetric organocatalysis.