1200592-00-2Relevant academic research and scientific papers
Novel syntheses of tetrahydrobenzodiazepines and dihydropyrazines via isocyanide-based multicomponent reactions of diamines
Shaabani, Ahmad,Maleki, Ali,Hajishaabanha, Fatemeh,Mofakham, Hamid,Seyyedhamzeh, Mozhdeh,Manyari, Mojtaba,Ng, Seik Weng
experimental part, p. 186 - 190 (2010/10/19)
In this work, two novel isocyanide-based mul multicomponent reactions of 1,2-diamine compounds with diketene have been developed as efficient strategies for the synthesis of 2,3,4,5-tetrahydro-lH-benzo[b][l,4]diazepine2-carboxamidcs with regiochemical control and 1,6-dihydropyrazinc-2,3-dicarbonitrilcs in good to excellent yields at ambient temperature.
