1200830-55-2Relevant academic research and scientific papers
Synthesis of some novel 5-(Arylidene)-2-imino-3(pyridin-2-yl)thiazolidin-4- one derivatives
Mobinikhaledi, Akbar,Foroughifar, Naser,Faghihi, Somayeh
experimental part, p. 1837 - 1842 (2010/02/28)
Treatment of 2-aminopyridine (1) with chloroacetyl chloride in dry benzene gave 2-chloro-N-(pyridin-2-yl)acetamide (3), which on further reaction with potassium thiocyanate gave 2-imino-3-(pyridin-2-yl)thiazolidin-4-one (4) as an intermediate compound for the synthesis of pyridin-2-yl substituted 2-imino-thiazolidine-4-one derivatives. Cyclocondensation reaction of (4) with a series of aromatic aldehydes gave 5-arylidene derivatives of pyridin-2-yl substituted 2-imino-thiazolidine-4-ones 5a-j. 1H and 13C NMR spectroscopy, as well as elemental analyses, were used for the identification of these new compounds.
