120090-33-7

Upstream product

• 108-24-7 acetic anhydride 
• 50908-04-8 (-)-Methyl-5-O-trityl-β-D-ribofuranosid 
• 16896-00-7 5-O-trityl β-L-arabinofuranoside 
• 532-20-7 L-arabinose 
• 3795-69-5 methyl β-L-arabinofuranoside 
• 7473-45-2 1-O-methyl-D-ribofuranose 
• 76-83-5 trityl chloride 

Downstream Products

• 120090-38-2 methyl 2,3-di-O-acetyl-5-O-(2,3-di-O-acetyl-5-O-benzoyl-β-D-ribofuranosyl)-β-D-ribofuranoside 

Relevant academic research and scientific papers

SYNTHESIS AND TRANSFORMATION OF DERIVATIVES OF THE N- AND O-GLYCOSIDES OF D-RIBOFURANOIC ACID

A method was developed for the nonselective oxidation of pyrimidine nucleosides and methyl β-D-ribofuranoside to the uronic acids by successive treatment first with triphenylchloromethane and then with acetic anydride in pyridine, followed by oxidation with chromic anhydride in acetone in the presence of sulfuric acid.The transformations of the obtained uronic acids into anhydronucleosides by the action of phthalimide and into 3',4'-unsaturated nucleosides by the action of 1,5-diazabicycloundec-5-ene are described.

N.M.R. SPECTRAL STUDY OF α- AND β-L-ARABINOFURANOSIDES

Anomeric pairs of L-arabinofuranosides of various aliphatic alcohols were synthesized and then investigated by n.m.r. spectroscopy.The 13C-n.m.r. glycosylatation shift of these L-arabinofuranosides is very similar to that of L-arabinopyranosides and other glycopyranosides reported previously.The 3JH-1,H-2 value of these α-L-arabinofuranosides is significantly different from that of the β anomers and can be used for the determination of the anomeric configuration.However, in contrast to the case of glycopyranosides, the 1JC-1,H-1 values of each anomeric series of L-arabinofuranosides are very similar to each other.Some disaccharides containing an L-arabinofuranoside unit were also investigated by n.m.r. spectroscopy.

SYNTHESIS OF METHYL 2-O-, 3-O-, AND 5-O-β-D-RIBOFURANOSYL-β-D-RIBOFURANOSIDE via 1,2-O-CYANOETHYLIDENE DERIVATIVES OF D-RIBOFURANOSE

Triphenylmethylium perchlorate-catalyzed glycosylation of 2-, 3- and 5-trityl ethers of methyl β-D-ribofuranoside by 1,2-O-cyanoethylidene derivatives of D-ribofuranose gave good yields of the corresponding 1,2-trans-linked disaccharide derivatives.The st