1201005-74-4Relevant academic research and scientific papers
Dimetallic Palladium-NHC Complexes: Synthesis, Characterization, and Catalytic Application for Direct C?H Arylation Reaction of Heteroaromatics with Aryl Chlorides
Lee, Jhen-Yi,Ghosh, Debalina,Kuo, Ya-Ting,Lee, Hon Man
, p. 648 - 658 (2020)
A series of dimetallic palladium(II)-NHC complexes comprised of 1,4-naphthalenyl or 9,10-anthracenyl spacer sandwiched between two imidazole rings was successfully synthesized. These complexes were characterized by 1H and 13C{1H} NMR spectroscopy and elemental analysis. The structures of two dimetallic palladium complexes and a related mononuclear palladium complex to be used for comparative studies were further characterized by X-ray diffraction. The dimetallic palladium complex with the 9,10-anthracenyl linker was very efficient in catalyzing direct C?H arylation reactions of heteroaromatic compounds (imidazoles, imidazo[1,2-a]pyridine, and thioazole) with a broad range of aryl chlorides, employing a mild monopalladium loading of 1.5 mol%.It allows for the effective use of aryl chlorides to prepare arylated heterocycles, previously only accessible with the more reactive bromide counterparts. Importantly, the catalytic activity of the dimetallic precatalyst was found to be higher than that of an analogous mononuclear complex. (Figure presented.).
A tridentate CNO-donor palladium(II) complex as efficient catalyst for direct C―H arylation: Application in preparation of imidazole-based push–pull chromophores
Li, Hui-Hong,Maitra, Ratnava,Kuo, Ya-Ting,Chen, Jie-Hong,Hu, Ching-Han,Lee, Hon Man
, (2017/09/06)
A series of imidazolium chlorides for the formation of tridentate CNO-donor palladium(II) complexes featuring N-heterocyclic carbene moieties have been developed from cheap and readily available starting materials with high yields. Their palladium complex
Phosphine-free palladium-catalysed direct 5-arylation of imidazole derivatives at low catalyst loading
Roger, Julien,Doucet, Henri
experimental part, p. 9772 - 9781 (2010/01/06)
The regioselective 5-arylation of imidazole derivatives with aryl bromides using a low loading of a phosphine-free palladium catalyst gives a simple and economic access to the corresponding 5-arylimidazoles. The choice of the base and of the solvent was f
